()-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate
(+|-)-Benzyloxycarbonyl-alpha-phosphonoglycine trimethyl ester
CAS: 88568-95-0
Molecular Formula: C13H18NO7P
()-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate - Names and Identifiers
| Name | (+|-)-Benzyloxycarbonyl-alpha-phosphonoglycine trimethyl ester |
| Synonyms | N-Cbz-2-Phosphonoglycine trimethyl ester ()-Z-alpha-Phosphonoglycine trimethyl ester (+-)-N-cbz-A-phosphonoglycine trimethyl ester N-Carbobenzoxy-2-phosphonoglycine Trimethyl Ester N-Benzylcarbonyl-alpha-phosphonoglycine trimethyl ester methyl {[(benzyloxy)carbonyl]amino}(dimethoxyphosphoryl)acetate ()-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate methyl (2R)-{[(benzyloxy)carbonyl]amino}(dimethoxyphosphoryl)ethanoate methyl (2S)-{[(benzyloxy)carbonyl]amino}(dimethoxyphosphoryl)ethanoate N-Cbz-2-phosphonoglycine Trimethyl EsterTrimethyl 2-(Carbobenzoxyamino)-2-phosphonoacetateTrimethyl 2-(Cbz-amino)-2-phosphonoacetate |
| CAS | 88568-95-0 |
| EINECS | 629-458-5 |
| InChI | InChI=1/C13H18NO7P/c1-18-12(15)11(22(17,19-2)20-3)14-13(16)21-9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,14,16)/t11-/m1/s1 |
()-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate - Physico-chemical Properties
| Molecular Formula | C13H18NO7P |
| Molar Mass | 331.26 |
| Density | 1.284±0.06 g/cm3(Predicted) |
| Melting Point | 77-80°C(lit.) |
| Boling Point | 480.5±45.0 °C(Predicted) |
| Flash Point | 244.4°C |
| Solubility | Soluble in methanol. |
| Vapor Presure | 2.16E-09mmHg at 25°C |
| Appearance | White solid |
| Color | White |
| BRN | 5764460 |
| pKa | 9.42±0.46(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.504 |
| MDL | MFCD00043304 |
()-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36 - Wear suitable protective clothing. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| HS Code | 29242990 |
()-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate - Reference Information
| Application | a-phosphonoglycinate is white crystalline or crystalline powder at room temperature, it is easy to dissolve in water, partially soluble in ethanol, ether and other organic solvents. (±) benzyloxycarbonyl-a-phosphonylglycine trimethyl Ester is its benzyloxycarbonyl protected product, can be used as a chemical intermediate, covering a wide range of applications, including pesticides, pharmaceuticals, food, animal feed and daily chemicals and other industries. |
| preparation method | A-phosphonoglycinate trimethyl Ester was added to A round bottom flask, and 10% sodium carbonate aqueous solution was added to stir and dissolve, then dioxane is added, and 10% dioxane solution of 9-fluorenylmethoxycarbonyl chloride is slowly added dropwise into the reaction solution in an ice bath, and the reaction is carried out in an ice bath for 2 hours after completion of the dropwise addition, then react at room temperature for 8 hours, dilute with water, extract with ether 4 times, place the water layer in ice bath, adjust the pH value with concentrated hydrochloric acid to Congo red test paper, in the refrigerator overnight, the white precipitate was extracted with ethyl acetate, the combined organic liquid was washed with water, the organic layer was dried with anhydrous magnesium sulfate, and was dried to obtain (±) benzyloxycarbonyl-A-phosphonylglycine trimethyl ester. |
Last Update：2024-04-09 02:00:12
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Product Name: (±)-Z-α-Phosphonoglycine trimethyl ester Visit Supplier Webpage Request for quotationCAS: 88568-95-0
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Mobile: 18021002903
QQ: 3008007409
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